Open Access

Abstract Background and purpose:Chromosomal aberrations in peripheral blood lymphocytes are a biomarker for radiation exposure and are associated with an increased risk for malignancies. To determine the long-term cytogenetic effect of radiotherapy, we analyzed the persistence of different aberration types up to 2.5 years after C-ion boost + IMRT treatment.Materials and Methods:Cytogenetic damage was analyzed in lymphocytes from 13 patients that had undergone C-ion boost + IMRT treatment for prostate cancer. [...]

Human embryonic stem cells (hESCs) differentiated into cardiomyocytes (CM) often develop into complex 3D structures that are composed of various cardiac cell types. Conventional methods to study the electrophysiology of cardiac cells are patch clamp and microelectrode array (MEAs) analyses. [...]