Record #188014 - GSI Repository

smartCC

Designing novel smart sensor interfaces based on a biologically abundant peptide motif: coiled-coils

Coordinator	MPG - Max Planck Institute for Human Development
Grant period	2017-06-01 - 2019-09-15
Funding body	European Union
Call number	H2020-MSCA-IF-2015
Grant number	705857
Identifier	G:(EU-Grant)705857

Note: Smart interfaces alter their properties in response to an external trigger. Such devices open exciting opportunities for novel technologies with manifold applications. Electrical fields pose easily controllable triggers for smart interfaces and even allow a precise 'digital' switching between 'on' and 'off' states. The research project ‘smartCC’ will employ a biologically abundant class of biomacromolecules – coiled-coil peptides – to prepare smart selective interfaces, whose ability to specifically bind targets can be switched reversibly. Moreover, the produced interface will constitute a highly sensitive sensor by application of the attenuated total reflection infrared reflection technique. The variability of coiled-coils, employed in numerous biological systems, will also extend the potential application bandwidth of smart interfaces significantly. Molecular details of the switching and binding behaviour of the coiled-coils at the interface will be studied to test the feasibility of the envisioned working principle. Furthermore, the novel devices will be tested for an application with industrial relevance. To reach the goals of ‘smartCC’ a highly interdisciplinary approach is chosen that includes cooperation between three academic and one non-academic European partners. Thus, the implementation of this project will support bringing an emerging technology towards an economical benefit, foster intra European collaborations and mobility as well as strengthen Europe’s scientific sector.

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Record created 2016-06-03, last modified 2023-02-12

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