Record #204666 - GSI Repository

ACEnano

Analytical and Characterisation Excellence in nanomaterial risk assessment: A tiered approach

Coordinator	Helmholtz-Zentrum für Umweltforschung GmbH - UFZ ; Technology Strategy Board ; VITROCELL SYSTEMS GMBH ; OSCUBE ; TO21 CO LTD ; BIOLIN SCIENTIFIC AB ; EDELWEISS CONNECT GMBH ; HORIBA UK LIMITED ; INDUSTRY-UNIVERSITY COOPERATION FOUNDATION OF HANYANG UNIVERSITY ; PerkinElmer Limited ; TOFWERK AG ; Universitätszahnklinik Wien ; Federal Institute For Materials Research and Testing ; BMEL - Federal Institute for Risk Assessment ; Natural Environment Research Council ; Postnova Analytics (Germany) ; JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION ; THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD ; Malvern Instruments Ltd ; CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT ; Swedish University of Agricultural Sciences ; Scisys UK Limited ; NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY, CHINA ; STICHTING WAGENINGEN RESEARCH ; NANOFUTURES ASBL ; University of Birmingham ; Swiss Federal Institute of Technology in Zurich
Grant period	2017-01-01 - 2021-06-30
Funding body	European Union
Call number	H2020-NMBP-2016-two-stage
Grant number	720952
Identifier	G:(EU-Grant)720952

Note: An increasing number of nanomaterials (NMs) are entering the market in every day products spanning from health care and leisure to electronics, cosmetics and foodstuff. Nanotechnology is a truly enabling technology, with unlimited potential for innovation. However, the novelty in properties and forms of NMs makes the development of a well-founded and robust legislative framework to ensure safe development of nano-enabled products particularly challenging. At the heart of the challenge lies the difficulty in the reliable and reproducible characterisation of NMs given their extreme diversity and dynamic nature, particularly in complex environments, such as within different biological, environmental and technological compartments. Two key steps can resolve this: 1) the development of a holistic framework for reproducible NM characterisation, spanning from initial needs assessment through method selection to data interpretation and storage; and 2) the embedding of this framework in an operational, linked-up ontological regime to allow identification of causal relationships between NMs properties, be they intrinsic, extrinsic or calculated, and biological, (eco)toxicological and health impacts fully embedded in a mechanistic risk assessment framework. ACEnano was conceived in response to the NMBP 26 call with the aim to comprehensively address these two steps. More specifically ACEnano will introduce confidence, adaptability and clarity into NM risk assessment by developing a widely implementable and robust tiered approach to NM physico-chemical characterisation that will simplify and facilitate contextual (hazard or exposure) description and its transcription into a reliable NMs grouping framework. This will be achieved by the creation of a conceptual “toolbox” that will facilitate decision-making in choice of techniques and SOPs, linked to a characterisation ontology framework for grouping and risk assessment and a supporting data management system.

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Record created 2017-06-14, last modified 2023-02-08

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