Record #205782 - GSI Repository

AIDViC

Antibiotic intracellular delivery via virus-like carriers

Coordinator	University of London - University College London
Grant period	2017-07-01 - 2018-12-31
Funding body	European Union
Call number	ERC-2016-PoC
Grant number	754704
Identifier	G:(EU-Grant)754704

Note: Taking inspiration from natural carriers, such as viruses, a new technology has been developed in our laboratories part of an ongoing ERC starting grant project, Molecular Engineering of Virus-like Carriers (MEViC). We created synthetic viruses using polymers and thus safer materials. They are able of delivering high payload of specific drugs into cells with no detrimental effect. While testing for anticancer therapies, we identified a synthetic virus capable of targeting almost exclusively macrophages. We performed preliminary work showing that this can be successfully applied to deliver antibiotics to rid of intracellular pathogens. This has now open a completely new possibility whereas we can expand our technology for the treatment of several infections as well as to contribute to the ongoing efforts in tackling antibiotic resistance.

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Record created 2017-07-24, last modified 2023-02-12

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