Record #242857 - GSI Repository

AMNIOGEL

Extracellular matrix derived products from human placenta to engineer bone microtissues for in vitro disease models.

Grant period	2020-09-01 - 2022-10-31
Funding body	European Union
Call number	ERC-2020-PoC
Grant number	957585
Identifier	G:(EU-Grant)957585

Note: The aim of ‘AMNIOGEL’ is the development of human extracellular matrix (ECM) based materials, as radically innovative, highly versatile human-derived platforms for 3D cell culture, microtissue development and disease models establishment. In particular, we will develop 3D disease models that could be used as an enabling tool for personalized drug discovery, increasing our understanding of the mechanisms behind bone cancer. The proposed cutting-edge technology enables the culture of human cells in a physiologically relevant microenvironment for applications in cell culture research, drug screening and development, cancer research, tissue engineering, replacement of animal testing and therapeutic applications. The potential of this technology to reduce or completely replace use of animals for biological screenings is expected to have a significant impact in the 3D cell culture market and pharmaceutical industry by accelerating drug screening and development reducing associated costs. The innovation potential of our products is based on the fact that contain human biochemical cues (vital for cell function), is a complete xeno-free solution (avoids contamination) for human cell culture and easy to manipulate. It is worth mentioning that offers the possibility to be personalised (using the patient’s own ECM) according to the customer needs. Moreover, our culture substrates are easily processed in multiple geometries and in microarrays amenable to ‘organ-on- a-chip’ systems designed for high-throughput screening (HTS) applications.

Recent Publications

There are no publications

Record created 2021-10-10, last modified 2023-02-14

Similar records

Add to personal basket
Export as Author List with IDs BibTeX (UTF-8), EndNote XML, EndNote Text, RIS, MARC, Print MARC, MARCXML, DC,
Request correction
Submit fulltext

GSI Homepage \| GSI Library \| English Deutsch \| guest :: login GSI Repository
Search	Submit	Personalize Your alerts Your baskets Your searches	Help