000341708 001__ 341708
000341708 005__ 20230827173324.0
000341708 0247_ $$2CORDIS$$aG:(EU-Grant)190133715$$d190133715
000341708 0247_ $$2CORDIS$$aG:(EU-Call)HORIZON-EIC-2022-ACCELERATOR-01$$dHORIZON-EIC-2022-ACCELERATOR-01
000341708 0247_ $$2originalID$$acorda_____he::190133715
000341708 035__ $$aG:(EU-Grant)190133715
000341708 150__ $$aBreakthrough Brain Stimulation Device for Epilepsy$$y2023-03-01 - 2025-02-28
000341708 372__ $$aHORIZON-EIC-2022-ACCELERATOR-01$$s2023-03-01$$t2025-02-28
000341708 450__ $$aBFORE$$wd$$y2023-03-01 - 2025-02-28
000341708 5101_ $$0I:(DE-588b)5098525-5$$2CORDIS$$aEuropean Union
000341708 680__ $$aEASEE® stands for epicranial application of stimulation electrodes in epilepsy. It is the first minimally invasive device for focal cortical stimulation. Based on the Laplace electrode (central electrode surrounded by a ring electrode), EASEE® features 4 distinct electrodes replacing the outer ring, connected to 4 independent current sources to account for impedance and anatomical variances in the human skull. Still, the characteristic quadrupolar local electric field with high penetration depth is maintained. 
The stimulation pattern is one of a kind. EASEE® is equipped for high frequency, DC-like, and low-frequency stimulation, depending on the condition to be treated. In epilepsy, intermittent high-frequency stimulation bursts throughout the day are combined with a 20min DC-like stimulation session. This first is meant to terminate upcoming seizures, the second to initiate neuromodulatory processes to down-regulate the overexcitability of the epileptic brain area.
000341708 909CO $$ooai:juser.fz-juelich.de:1011067$$pauthority:GRANT$$pauthority
000341708 909CO $$ooai:juser.fz-juelich.de:1011067
000341708 980__ $$aG
000341708 980__ $$aCORDIS
000341708 980__ $$aAUTHORITY