Record #343486 - GSI Repository

OPERAS

Opioid-free Pain relief for Enhanced Recovery After Spine fixation surgery

Grant period	2023-04-01 - 2026-03-31
Funding body	European Union
Call number	HORIZON-EIC-2023-ACCELERATOR-01
Grant number	190122961
Identifier	G:(EU-Grant)190122961

Note: There is a troubling lack of effective pain treatments after major surgery. Especially after musculoskeletal procedures, patients experience debilitating pain now treated with opioids. Opioids provide insufficient pain relief, have many toxic side-effects, and are highly addictive. Pain and opioid-related side-effects impede early mobilisation and recovery and are the primary reasons for extended hospital stays. SentryX is developing revolutionary drug delivery technology to extend the effects of a well-established local pain blocker called bupivacaine. Its initial use case in spine fixation surgery, Bupi-Ring, delivers bupivacaine directly to the surgical site for more than 72 hours without changing the existing surgical workflow. Non-opioid local pain relief in this critical early phase of recovery will promote early mobilisation, shorten hospital stays, prevent complications, and save costs. This project will demonstrate Bupi-Ring’s safety and efficacy in humans for the first time.

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Record created 2023-08-27, last modified 2023-08-27

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